G6PD缺乏症避免使用的藥物

MIMS Summary TableMIMS Summary Table
DRUGS TO AVOID IN G6PD DEFICIENCY
DEFINITE RISK OF HAEMOLYSISDEFINITE RISK OF HAEMOLYSIS		POSSIBLE RISK OF HAEMOLYSISPOSSIBLE RISK OF HAEMOLYSIS
Pharmacological ClassPharmacological Class	Drugs*Drugs*	Pharmacological ClassPharmacological Class	Drugs*Drugs*
AnthelminticsAnthelmintics	• ß-Naphthol • Niridazole • Stibophen• ß-Naphthol • Niridazole • Stibophen	AnalgesicsAnalgesics	• Acetylsalicylic acid (Aspirin) • Acetanilide • Paracetamol (Acetaminophen) • Aminophenazone (Aminopyrine) • Dipyrone (Metamizole) • Phenacetin • Phenazone (Antipyrine) • Phenylbutazone • Tiaprofenic acid• Acetylsalicylic acid (Aspirin) • Acetanilide • Paracetamol (Acetaminophen) • Aminophenazone (Aminopyrine) • Dipyrone (Metamizole) • Phenacetin • Phenazone (Antipyrine) • Phenylbutazone • Tiaprofenic acid
AntibioticsAntibiotics	• Nitrofurans - Nitrofurantoin - Nitrofurazone • Quinolones - Ciprofloxacin - Moxifloxacin - Nalidixic acid - Norfloxacin - Ofloxacin • Chloramphenicol • Sulfonamides - Co-trimoxazole (Sulfamethoxazole + Trimethoprim) - Sulfacetamide - Sulfadiazine - Sulfadimidine - Sulfamethoxazole - Sulfanilamide - Sulfapyridine - Sulfasalazine (Salazosulfapyridine) - Sulfisoxazole (Sulfafurazole)• Nitrofurans - Nitrofurantoin - Nitrofurazone • Quinolones - Ciprofloxacin - Moxifloxacin - Nalidixic acid - Norfloxacin - Ofloxacin • Chloramphenicol • Sulfonamides - Co-trimoxazole (Sulfamethoxazole + Trimethoprim) - Sulfacetamide - Sulfadiazine - Sulfadimidine - Sulfamethoxazole - Sulfanilamide - Sulfapyridine - Sulfasalazine (Salazosulfapyridine) - Sulfisoxazole (Sulfafurazole)
		AntibioticsAntibiotics	• Furazolidone • Streptomycin • Sulfonamides - Sulfacytine - Sulfaguanidine - Sulfamerazine - Sulfamethoxypyridazole• Furazolidone • Streptomycin • Sulfonamides - Sulfacytine - Sulfaguanidine - Sulfamerazine - Sulfamethoxypyridazole
		AnticonvulsantsAnticonvulsants	• Phenytoin• Phenytoin
		AntidiabeticsAntidiabetics	• Glibenclamide• Glibenclamide
		AntidotesAntidotes	• Dimercaprol (BAL)• Dimercaprol (BAL)
		AntihistaminesAntihistamines	• Antazoline (Antistine) • Diphenhydramine • Tripelennamine• Antazoline (Antistine) • Diphenhydramine • Tripelennamine
AntimalarialsAntimalarials	• Mepacrine • Pamaquine • Pentaquine • Primaquine• Mepacrine • Pamaquine • Pentaquine • Primaquine
		AntihypertensivesAntihypertensives	• Hydralazine • Methyldopa• Hydralazine • Methyldopa
Antimethemo- globinaemic AgentsAntimethemo- globinaemic Agents	• Methylene blue• Methylene blue	AntimalarialsAntimalarials	• Chloroquine & derivatives • Proguanil • Pyrimethamine • Quinidine • Quinine• Chloroquine & derivatives • Proguanil • Pyrimethamine • Quinidine • Quinine
AntimycobacterialsAntimycobacterials	• Dapsone • Para-aminosalicylic acid • Sulfones - Aldesulfone sodium (Sulfoxone) - Glucosulfone - Thiazosulfone• Dapsone • Para-aminosalicylic acid • Sulfones - Aldesulfone sodium (Sulfoxone) - Glucosulfone - Thiazosulfone
		Antimycobacterials	• Isoniazid
		Antiparkinsonism Agents	• Trihexyphenidyl (Benzhexol)
Antineoplastic Adjuncts	• Doxorubicin • Rasburicase	Cardiovascular Drugs	• Dopamine (L-dopa) • Procainamide • Quinidine
Genitourinary Analgesics	• Phenazopyridine (Pyridium)	Diagnostic Agent for Cancer Detection	• Toluidine blue
Others	• Acetylphenylhydrazine • Phenylhydrazine	Gout Preparations	• Colchicine • Probenecid
		Hormonal Contraceptives	• Mestranol
		Nitrates	• Isobutyl nitrite
		Vitamin K Substance	• Menadiol Na sulfate • Menadione • Menadione Na bisulfite • Phytomenadione
		Vitamins	• Ascorbic acid (Vit C) (rare)
		Others	• Arsine • Berberine (in Coptis chinensis) • Fava beans • Naphthalene (in mothballs) • Para-aminobenzoic acid
*Nomenclature based on INN (International non-proprietary name)
Refer to www.g6pd.org for further information.
Please refer to the Contents page for more Summary Tables.
Copyright © 2006 MIMS
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資料來源：財團法人嘉義基督教醫院 http://www.cych.org.tw/pharm/searchdrug.aspx
以上資料只作參考之用，詳情請諮詢醫生

香港蘋果日報:止嘔藥Domperidona 兩歲以下不宜服用

香港蘋果日報
A12 | 港聞 | 2015-02-27

止嘔藥Domperidona 兩歲以下不宜服用

【專家之言】

對於澳門五個月大患有蠶豆症男嬰猝死，醫生被指開錯藥，有香港藥劑師指涉事的兩種藥物，其中一種止嘔藥不建議供兩歲以下嬰孩服用，在外國更有警告指長者服用可致死亡；但有心臟科醫生稱兩種藥物均不是蠶豆症禁服藥物。

加國︰長者服用可致命

香港醫院藥劑師學會會長崔俊明指，止嘔藥Domperidona可治療腸胃不適及作嘔作悶。今年一月，加拿大衞生當局發出警告，指六十歲以上長者服用此藥，可引致心律不齊、心臟停頓及突然死亡等風險。而本港醫生使用此止嘔藥，一般建議兩歲以上小孩才可服用。但崔表示，醫生有權為兩歲以下嬰孩處方此藥作「非適應症治療」，但必須同時向病童父母表明風險。

心臟科醫生何鴻光稱，蠶豆症病人一旦服錯藥致病發，會出現溶血症致貧血，會致全身黃疸、小便轉色等病徵，即使有致命風險，亦非半日內會發生，「多幾日先會有事」。對於蠶豆症，醫學界有一禁用藥物列表，但涉事兩種藥物均非列表內，其中止嘔藥更屬常用藥物，會按醫生臨床判斷是否處方予病童。

■記者龔蕙芝

資料來源：G6PD 缺乏症/蠶豆症資訊站
https://www.facebook.com/G6PD-%E7%BC%BA%E4%B9%8F%E7%97%87%E8%A0%B6%E8%B1%86%E7%97%87%E8%B3%87%E8%A8%8A%E7%AB%99-215564885253417/?fref=ts
以上資料只作參考之用，詳情請諮詢醫生